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N-Of-1 Trials Made Easy!

StudyU is the only available fully‑functional platform
for personalized N‑of‑1 treatment advice.

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Discover the Power of N-of-1

N-of-1 trials enable participants to discover the individual effects of interventions on their health. StudyU provides the supporting digital foundation.

Personalized by Design

N-of-1 trials focus on the individual – and so does StudyU. Conduct your own studies or partake in others. It's your choice.

Open Source for Everyone

StudyU is developed completely open source with self-hosting capabilities, guaranteeing a maximum of transparency and data privacy.

The StudyU Platform

StudyU Designer

The StudyU Designer is a web-based application supporting the design and implementation of digital N-of-1 trials for clinicians, researchers, or digital health enthusiasts. With its user-centric design framework, the StudyU Designer improves usability with many supportive features during the study creation process. Notably, it includes a preview function that provides a real-time visualization of the study design. Besides running private N-of-1 trials, seamless collaboration with other researchers is also supported by sharing studies, fostering collaboration and transparency in the spirit of public health and open science.

Refer to our tutorial to learn how to conduct your first digital N-of-1 trial or start designing your own study at

Screenshot of the StudyU DesignerScreenshot of the StudyU DesignerScreenshot of the StudyU Designer

StudyU App

The StudyU App is a user-friendly application that enables individuals to actively participate in digital N-of-1 trials and obtain personalized treatment advice. Its accessible design approach accommodates users with limited technical skills, allowing them to directly measure the impact of interventions on their health outcomes. By engaging patients in the trial process, the StudyU App promotes patient empowerment and facilitates shared decision-making between researchers, clinicians, and individuals. The StudyU App leverages the capabilities of statistical computing and advanced machine learning models to identify the optimal intervention tailored specifically to your unique needs and circumstances.

Have a look at our tutorials to learn how to use the StudyU App as a general practitioner or participant. StudyU is available as a mobile application and as a web version at

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Screenshot of the StudyU App

StudyU in collaboration with clinical studies

HPI Mount Sinai
Mount Sinai
Weill Cornell
University of Queensland
Universitätsklinikum Hamburg-Eppendorf
Uniklinikum Würzburg
Robert-Bosch-Krankenhaus Stuttgart
University of Health and Allied Sciences, Ghana

Recent Blog Posts

StudyU at the 2nd Spring Symposium on Medical Informatics in Heidelberg
Johannes Vedder presenting the StudyU platform at the 2nd Spring Symposium on Medical Informatics in Heidelberg

On May 8th, 2024, Johannes Vedder, senior developer of StudyU, presented the StudyU platform at the 2nd Spring Symposium on Medical Informatics in Heidelberg, Germany.

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Innovative Anti-Stress Study among Physicians at Charité

The "Anti-Stress Intervention Among Physicians (ASIP)" Study utilizes StudyU to investigate the following intriguing and pertinent research question:

How can the everyday level of perceived stress be reduced in a fast and easy-to-implement manner?

The project will be conducted in cooperation with the Institute for Public Health at Charité – Universitätsmedizin Berlin (Principal Investigator: Dr. med. Valentin Vetter).

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StudyU's Role in Easing Antidepressant Discontinuation in the FAB-Study

We are pleased to announce the publication of the first research paper utilizing the StudyU platform for a medical study. The paper Study protocol: combined N-of-1 trials to assess open-label placebo treatment for antidepressant discontinuation symptoms [FAB-study] was published in cooperation with Universitätsklinikum Hamburg-Eppendorf and Universitätsklinikum Giessen und Marburg, both of them based in Germany.

Let us have a deeper look into the content of this innovative study and what this achievement means for StudyU.

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Introducing StudyU to the German Federal Minister of Health
Dr. Stefan Konigorski showcasing the capabilities of StudyU for personalized healthcare interventions to the German Federal Minister of Health, Prof. Dr. Karl Lauterbach

On June 8, 2023, we had the honor of introducing StudyU to Prof. Dr. Karl Lauterbach, the German Federal Minister of Health, during his visit to the Digital Health Cluster at the Hasso Plattner Institute (HPI).

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StudyU has won the Best Idea Award 2022 at HPI
The winning team StudyU with Pauline Gieseler (middle left) and Johannes Vedder (middle right)

StudyU has won the Best Idea Award 2022 of the School Of Entrepreneurship at Hasso Plattner Institute (HPI). The team consists of Pauline Gieseler and Johannes Vedder, who are both students at the Hasso Plattner Institute in Potsdam, Germany.

Winning this award grants us the opportunity to visit HPI New York City and meet its director, Dr. Joann Halpern. Additionally, it enables us to establish connections with HPI・MS, a collaborative project between HPI and Mount Sinai Health System, renowned as one of the world's top-ranked hospitals.

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